Frequently Asked Questions

FAQ

Find answers here about our platform capabilities, usage, technical details, kit integrations. Should you need any additional info, feel free to contact us at your convenience, we look forward helping you with your diagnostic and research applications.

Topics

How can I connect to bCUBE® ?

bCUBE® communicates over two main channels: Wi-Fi and Ethernet. Ethernet connection is required for first setup. bCUBE can be controlled directly from a Smartphone using the Mobile Hotspot functionality of your device.

Which type of device can be used for controlling bCUBE®?

bCUBE® can be controlled from any device with internet connection, including Desktop PCs, Laptops, Tablets and Smartphones. Offline use is possible using bPANEL interface, for Windows PC.

Can I use bCUBE® everywhere in the world?

Absolutely! The supplied power source works at both 110V and 220V, and the power cord can be easily interchanged with the one compatible with the standard of your destination country. Moreover, you can monitor in real-time and control remotely all of your bCUBEs thanks to their connection to Hyris bDATA(r) service.

Do I need to be an expert Biologist in order to use bCUBE®?

No, you don’t. bAPP’s extremely intuitive interface will guide you through every step of the setup and analysis. You’ll be able to start your analysis with only a few simple touches, and our automatic results interpretation engine will assist you in determining the outcome.

Can bCUBE® be used for laboratory/research use?

Yes. With Hyris bAPP you can create custom protocols, run thermal cycling or isothermal protocols, perform high resolution melting analysis, and scan all your samples at the same time. With bCUBE®, even the most demanding biologist will be satisfied. Moreover, bCUBE® offers the unique possibility to integrate automatic results interpretation in its recipes, and Biologists can have their recipes/applications published on Hyris platform and made available to all bCUBE® users in the world, boosting their reach of potential customers.

Can bCUBE® perform thermal cycling?
Yes. bCUBE® is capable of running custom thermal cycling protocols, maximizing ramp speed, and running Real Time PCR analyses. Moreover, its flexible thermal control algorithm is able to keep a constant temperature profile, thus maximizing stability and precision, and giving outstanding performance in isothermal amplification protocols.
Can bCUBE® run Melting analysis?

Yes. bCUBE® can control slow temperature ramps very precisely, and the resolution of its temperature sensor (< 0.05°C) enables melting analyses with very high resolution.

What fluorophores are compatible with bCUBE®?
At present, our standard model is compatible with FAM and VIC fluorophores (and all equivalents). In addition, due to the modular nature of its patented technology, a custom optical design can be requested to make bCUBE® compatible with virtually any type of fluorophore.
Can bCUBE® detect multiple wavelengths in a single analysis?

Yes. bCUBE® is able to scan all samples simultaneously for each of the installed wavelengths (FAM and VIC fluorophores for the standard model). This allows analyses with multi-targets or an internal control.

How can I get support/assistance?

For quick response on technical questions, you can use our ‘Contacts’ section on our website. If you have software issues with the instrument, we can provide remote assistance by connecting directly to your bCUBE® via the internet. Moreover, bCUBE® will receive periodic remote updates in order to always guarantee state-of-the-art performance and features.


What are the compatible operating systems and devices?

Our bAPP is compatible with MacOS, iOS, Android, Linux and Windows operating system. It doesn’t need installation, the only requirement is to have installed on your device one compatible web browser (suggested browsers: Chrome / Safari). It can be used with Desktop PCs/Laptops, Tablets and Smartphones.

Do I need to stay connected and nearby bCUBE® for the entire analysis?

No, you don’t. As soon as the analysis is started, bCUBE® is able to carry it to completion entirely without the need of any interaction from you. If you like, you can even go for a coffee and check your experiment in real-time remotely from your Smartphone, thanks to bDATA service. You can also turn it off from home after the experiment is completed.

What happens if I lose the connection or my phone battery goes low during an analysis?

No worries, it won’t affect the analysis. As long as bCUBE® is connected to the internet, you can monitor the results in real-time from any device connected to the web. If bCUBE® is offline, it will sync all its pending results as soon as it goes back online.

What are the advantages of controlling bCUBE® through bAPP?

With bAPP, genetic detection becomes remarkably easy. Your analyses can be entirely portable: just bring the small bCUBE® and a smartphone to set up in your laboratory or in the field. You can take pictures, record GPS coordinates, and link them to each sample you’re analyzing, while obtaining results within just a few minutes. Our results interpretation engine will assist you in determining the outcome of the test, without the need to be an expert in genetic detection.

Do I need to be outside of buildings to get GPS reading?

No. By exploiting the smartphone’s A-GPS, your location can be acquired through your mobile network or Wi-Fi. You can even set it manually on the map if you need.

How can I share my results?

bCUBE® automatically syncs all its experiments in real-time with bDATA service. This data can be seen by all the users you’ve given the permission to. A PDF report of each analysis can be automatically generated for easier sharing through email or other means.

How do I get the bAPP on my device?

bAPP is permanently hosted at https://bapp.hyris.net, or just follow the link on our website www.hyris.net

What is bDATA?

bDATA is the Hyris cloud service which collects all the data coming from all bCUBEs deployed in the world. Thanks to bDATA, all of your experiments performed using bAPP will always be available, and you’ll be able to analyze your data in aggregate form using our ever expanding manu of statistical representations. bDATA enables also the remote control and monitoring of all your machines at the same time.

Does bCUBE® need internet connection to operate?

No, bCUBE® can be operated also ‘offline’ using bPANEL software for Windows PC. All the experiments performed offline will anyway be synced to bDATA the Hyris cloud database the next time bCUBE® will be connected to the internet.

Does bAPP need access credentials?

Sure, this is required to make your data private. As soon as you register on our portal, an ‘Administrator’ account is created. This account will be able to create additional users, with the same or lower privileges, which will have total or partial visibility of your data, according to your needs.

Is my Experiment’s data visible to anyone?

No, your data is visible only to you, and to all the users of your organization with the proper permissions. Please note that a part of qualified Hyris staff will have access to this data in order to give you remote support when needed.

What is a ‘Swarm’?

One of Hyris platform’s major advantages is data aggregation. If you purchase multiple bCUBEs, you can see all the data coming from all of your machines in a single view, thanks to bDATA common database. In addition to this, we offer the possibility to organize bCUBEs in multiple ‘Swarms’, and to create users which have access only to one (or more) of these ‘Swarms’. These users will be able to see the data and to control only the bCUBEs of their Swarms, while the ‘Administrator’ users will always see all the data coming from all machines.

I heard I can get third party certificates when using the bCUBE®?

This is correct. Hyris partners with major reference labs and certification companies to offer a decentralized, lightning fast certification service: perform the analysis within your supply chain or premises using authorised reagents and protocols, upload the results onto our bDATA platform, and obtain your certificate sometimes in minutes.

What are Global Recipes?
While you can set up any experiment or reaction you wish and have absolute freedom is customising your R&D reactions, Hyris offers for download on its bAPP platform so called Global Recipes, I.e. set protocols determined by Hyris (sometimes in collaboration with the diagnostics kit manufacturer) which cannot be edited by the user. This guarantees the integrity of the data and the conformity with manufacturer’s specs and qualification tests. Global Recipes are used always for the Certification services provided by third parties.

What is a bKIT?

bKITs are reagent sets used to analyze a specific genetic sequence. They can be used e.g. for the detection of a pathogen in a biological sample, the correct identification of the nature of the sample and a large number of other purposes. Hyris both develops bKITs in its own R&D center, or adopts third party reagents after a stringent qualification process, thus greatly increasing the number of potential applications easily ported unto the platform.

My desired application is not listed in the available bKITs. How can I solve?

Hyris welcomes inquiries regarding customised projects, i.e. will evaluate requests to develop specific reagents (bKITs) for applications not yet present in our Catalog.

Is bCUBE® compatible with bKITs only? I am already using my reagents and protocols and I’m happy with them, can I keep everything?

Absolutely yes. The bCUBE® instrument and its custom cartridges are fully compatible with reagents used with standard laboratory instrumentation, and little to no tweaking is needed for porting your reagents. Our biological lab support team can help you with setting that up in no time.

We are a company selling reagents, can we use bCUBE®?

Hyris partners with providers of testing kits, enabling them to package a very attractive offer for their clients, and more importantly to significantly expand their client base. Due to the bCUBE® reduced cost and ease of use, the barrier to entry for new entrants are significantly reduced. We welcome inquiries from reagent companies regarding partnership proposals, including turning they testing kits into qualified bKITs.


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